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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '495ff6aff098f815f32bcadb32b40991901c1484c7a4aae8920f42f37ee5258d' 
  AND token = 'gz+5nX6uYP6wxhEjTsDONcH4lUiLe9RHBnnUtN9EkmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}