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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0cbf491cb126b6ac4e866a8a90f3b4a70f9fffc00e213c97ec36489c82fa504' 
  AND token = 'uQAQjAcpa5mFGh1jvBSXENmFZh2uLwRdwY1eGXKE3dE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}