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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5f16ffb1d5207b7e94408e3562179dfee183f74b485dc493b12de5314a641d9' 
  AND token = '+GrmPUT1M69aoj3cXZ9i1lSEaOOgMm/xhB6BXrlUpxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}