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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55125df63b4b9827362b7694dd475f641f1b5dd8c80b34475e96b1c1c7c29cba' 
  AND token = 'AgNTkyMeCc3qGr2dqKnLHKksZiZPLOxHIC4q8DA5g4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}