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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f59ffdd308aab7980fa8acfda0310810220d87a7ea04e09f656544f894880b6' 
  AND token = 'Ijy4B7MG9Bnq251zzkP8kkVj+E9kF5JfAFe+1lOv/ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}