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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e5b5ce2a31e84fcbd9d61496027b88538cc89d33a2040c8ee98b8464c0f0f1d' 
  AND token = 'GfNTT9WhAFDiDCoyIv6AsZg+tOVNa3GAkV+SCDtyA8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}