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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40ca36cd60be6519eecfd3895f930c2f74bf4a6197926593e46c08e76ebebc87' 
  AND token = 'r3XSt3WDfdfyPDa2wtM67rm32H0S6+DmypuZidP7ByE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}