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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc22e769de791e8a5f306db40057e7cd692af53378f9ea25a4e6a3a86654cf7' 
  AND token = 'HeeEhDbUAJEo7xpRsWa1O8Jw/KJqOIqRU38cZdmKLiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}