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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c123a9ee496ce6d050d28162f0e91bfa45bd585b41803d97c17a6847b20f32f1' 
  AND token = '+kZ+Y8W9mmUgT/p1lRTwIEshh8lTKZs5K30fCdEzbl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}