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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0971c49ae773c8a4ed3a4618aec1254f08fb0cf6443ba6c8749d0a6151a1592b' 
  AND token = '2d/NJfSCfoHXkmxTbdN/XXBGGnn9gPA+fR8Y0YdBL7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}