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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f0e8012025e04a3fb870b5386f13e9783563a474d906d3ef6a6d11a122d59a6' 
  AND token = 'uwbY7o9o3cjjGqjyPiR0tzh6iGk09HFl2b2LV5/yoTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}