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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d7dfcf60b64fe2341a5eb8daa02a907fec9478f25e9f9afa0e20b420ef54b28' 
  AND token = 'sxxdragohiqUmd40NmafClKPOwjjnPdzEswd5QiyM3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}