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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5fe79806185fd293d8812e39972e4e482197b2ae8d6ab61c613c7e4e2c80e1' 
  AND token = 'V4GOhpBLGHipJ7FHiuAeZsKXZ50pa2T0CQaLAAnF5aY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}