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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d1d203baadbb747f2229a4561cd702c7b31f6f60f8501e541abf6854a8f460d' 
  AND token = '+O2pB9JT6ORJTSV1RnrvWOwT2TM2ugrz8BfkmqOJADE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}