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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f0117e7a7e75824a77a652dbdcb0f85dd066b4ac125b550cb36dc93478219b' 
  AND token = 'JTCug38em2JyJRvXj1xkERNHRNEtqnVyv0gzTQVQC6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}