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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2cf3272454cf94324e10da557439cac065b8239dba0933daa0d12432aeb2330' 
  AND token = 'nQ1rz5kbFzh4g25zCxKOWRwV7zMkw1K8Nt2DNeFICZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}