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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2f17ec16e5863d884be9252a343cdbc97ecc418ebce9e7e029dc839eb43d798' 
  AND token = 'SlW4TCSz7jYIq3z/k1zDuQWL7SDb10O2YzCERV4Z7xU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}