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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2581b6aa2a6c057608f7949ff4003f9ca8cf435551f83e1f9965a1e48b4c7e4e' 
  AND token = 'BkOwZyRub4XCkV/05rSQxU1LLpXfrvdrVQ98MWa7ym4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}