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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd275f56e8477c7b9faab67007ffc00c32d8fb5cccd1e6466acfa1f79d41e8946' 
  AND token = '66lpkf0pF8XEgBB2UNTVaqMe/IChavmWDyy6svvS2NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}