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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bccd26d14ae85d76a6944639c1f9951f5e925361ee6d3180e9b047f12db5c0f' 
  AND token = '0a9Vd0jvayfPe+WGCKrhl3Z4GQ6DdwUnRvuC53lsjEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}