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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe343c88b8fb2693f2306aa2595cd2a5f17a1aae2887fe22496a80a6b75378a' 
  AND token = 'd0vQ6o2m6CLwITtGVA/eYYKHMWzKtzsWq90KXYrA0b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}