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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1306ded3bb0e064957e38d16a7dee147d3ab778f70adb817c92fb47787050ad' 
  AND token = '4el8Qj0I+RWskAHoxM9El1FdHymTagf1VIUs+XoCLu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}