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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eeef0b3825d90450c781215e4e6dbe5b4807ac3a88871fb64c2bc650f74acc7' 
  AND token = 'Eg6jwhNNvFkhdV5PVlvMC7QyBzW4242mWg9OMWvO8og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}