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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1703378567921499b8a4a1d41ee99de8728c8629cc6a42ac6fdefe486890f6' 
  AND token = '4KYUN0d1ngsNhb1/NMFW65PCCTewbBsHr0MIoCVcd5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}