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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae065a504e166b982d5e6e309d852374bf9d01fdd7b42c203f57aa9ec87e4696' 
  AND token = 'H20Lzt5h01SnRcIwpywIOdn5l2AKKMbu4Jpqw3ZTkk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}