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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6516b08439e63981c0d66db477cc0e48c2e99f9e36466e9a9053ac0dfcb0983' 
  AND token = 'nKJC7rTKrS5qrz6wqeItmBvE3bqy1NuyBBRSAWsMu8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}