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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1139b146f0e165fe2a793f053f8c9b3de1777009b6b7c2deabfedf43fb800ad0' 
  AND token = 's8NezFp+hcRl82cf70b1flh/XVe2TnFNTZ8bjsrl9QQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}