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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943b51c2221de42da0118607dde877b4a08da3ea0ff1bb97c73ff5dba968d226' 
  AND token = '3gJPlO/kg58yyAZELMhcQQFS7n4GUClXr66Q0ux5w1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}