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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49bc8f6fc2d55a034cc1c1329662117405e378f46efc67bf513bf6c03d49a17' 
  AND token = 'BgS1Pzj7+GtcURdCYn4557MD+5wKo6dCMVK1lMKrjz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}