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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ebdd2e2f69e2e5c9860e1dec2123847aa4273afdab8a5ca177879fc67a67b85' 
  AND token = 'A6+TVcTc+VQZ2Xd7f5zANu3dT3/a1gU/ATU3atWAMZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}