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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e01b871a0d1eeaae2f67107ee00fb6f9266fff23a03c2ce41428476e4865ff2' 
  AND token = '39s4VDx2UtfDReoLoPb7zOz078VTdS1zAPgIZ6p9TCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}