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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e72bc0e3be41315788fb3b68339bb10a8b68fe551d5a9856af996077ba52ea0' 
  AND token = 'ERoXkYY+opOJc8TbqppuIyBEz4Kj4L1YFRS6LCOFFB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}