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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40dde3f4cbfaaf8bf9dae194b50758062fa074776a36b3d99ed3d229ced2d04d' 
  AND token = 'CnL3cFUb2EEh7rDKhI2n+0hcoYyMzg1DybXZxMHkHVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}