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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57e081667021309cb7ac84f30ea753aeb5688a62e2b200e58c70748f2090cd06' 
  AND token = 'CnUgz5Jo4BbL1MZBUdiwVCAl6Mlw1sRYWc9YeTzIiTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}