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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24ad2b1dbd0969294ba0cde18c29db76dceba3453d53ed7f799040fcbe9b1936' 
  AND token = 'SEM4APZsRM6pEgp0rJ3as1DC79XdTRZpYYnyluH+rfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}