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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49930eeb31a2e0952652278b2511e7e306ea60e6c73d8a281567c65eebe87d5f' 
  AND token = 'gZpStvgwAxERiYZgXlx6eBL9IH5+cSLhf3P8C+KUQwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}