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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dd751b487d2472d8168224773e21558d67b03af29061f49b3e1239e836e6bc2' 
  AND token = 'Lo+qCeD2tMXpLxhbd0UjH1CZ9Y1Q3edKYbyvVOnRZbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}