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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe7bdecc55ac50b306d8415818a55b2ee2142d6ebbdcc7069dfd583610d56674' 
  AND token = 'hnHCI4VwDkR4BBb8xtoti1J6WoQtrHjcPC2LOvZ4Eno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}