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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3986ed2602dacfb6f5bb318947dce5d563e2ab714ebceb0a51d2b5f2b4b0d31e' 
  AND token = 'rN2P0mzUXcChbC8p9je/4SS4/ytOpLz1x7INAUMk8VQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}