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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5272b5e61fffe74bc1830126462e54faf0cf49ebc755634c016cb47c9f3b1923' 
  AND token = 'UXt+qPxehUQp3eifVCTT6WzRszAsuejUuCkZfmqgBP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}