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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0ccac3d51e9079b56b3e756f2b116761d73cf27020a4968ff19a0278c2dd614' 
  AND token = '3puLrydvIlFpxrkumEUAjukBukMNgmwDwShog+1X5iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}