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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4812b568b010cc2b8ecf63f81c0788a0d663491cc1422f76f269b1bf2f15252a' 
  AND token = 'yBWfmaA9Db4D6UNa4W0reFJd+N1U4XBQz2VvBf7Azj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}