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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa28429cffe95cc684e122ca90a8788c5ae7d3eda2a77f8edcd891a861fed37c' 
  AND token = 'oCRU8qNDh2xLXx9lSzGcmdx+5GRAEp8Y/9Deau39o0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}