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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a651aab685c17a51106c71819d471951bae30c6c6811c5d21598af4aeee035' 
  AND token = 'xBg6lJaNugy1r+dd3s7rYQ4zRhcaQdKSizTkxFl7qmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}