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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '448a1dbdf24ae086186c5522bee13e2abb3d222f00bb57956d813f5d0ce38550' 
  AND token = 'GuT0etHCCJEX+nHSUehvlpDSFmPAj8Jil7YUqAvFlpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}