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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad2d713b50831513f1032794cbf5710d0f0433544f11959d1905615efb359309' 
  AND token = 'Ll25e+PFVxNphCslw+VxkuEbEcPtyrGSZ6Gu8RTPMHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}