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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad8e9a9a9a5825889809158a0a496257b30b8de404dd1a19fe9781e6c0c5fc9e' 
  AND token = '6ac2Qfiv+vt+91yBd9UYoiDeUIkCVx7YEynDYqG0m7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}