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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2fa703e69f7633acdd820a73320227480aa35975696f81ff634836f5e0a129' 
  AND token = '1mFTUPzzdk6dWIGEzLEZp4/mrdwIva3gG9BwvuSEdDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}