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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c82e3e226529728efceb86990dbe9d79e5f310c7957f5fd1fe717e1bde4e544' 
  AND token = 'zcOhIVA2bDe1UyLUrurvpzK6UhTTwSqaryYXUBwv5Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}