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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16afdc86f4f14bea8cbd1caf8fa6ff3923b1c1e0d2a28a38037a31d87925bb16' 
  AND token = 'FwTaOb13amlsiN1oAK6Xr60eMYpBJ9434TbOOoeKZkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}